Anionic polymeric drugs

Anionic polymeric drugs Download PDF EPUB FB2

Anionic polymeric drugs (Polymers in biology and medicine) [ Donaruma] on *FREE* shipping on qualifying offers. Anionic polymeric drugs. New York: Wiley, © (OCoLC) Online version: Anionic polymeric drugs.

New York: Wiley, © (OCoLC) Document Type: Book: All Authors / Contributors: L Guy Donaruma; Raphael M Ottenbrite; Otto Vogl. This book presents these important facts: a) The mechanism of anionic polymerization, a more than year challenge in polymer chemistry, has now become better understood; b) Precise synthesis of many polymers with novel architectures (triblock, multi-block, graft, exact graft, comb, cyclic, many armed stars with multi-components, dendrimer-like hyper-branched, and their structural mixed (co.

Abstract. Polyanions are polyelectrolytes with negative charges that reside on pendant groups attached to the backbone of the polymer chain. Both natural polyanions such as heparin and heparinoids and synthetic polyanions such as polyacrylic acid and pyran produce a variety of biological activities which have been discussed in detail [1,2].Cited by: Synthesis and Self-Assembly of the pH-Responsive Anionic Copolymers for Enhanced Doxorubicin-Loading Capacity Meijun Yi Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, College of Chemistry and Materials Science, Cited by: 3.

Cationic Polymers in Drug Delivery rifampin, an anionic antibiotic used to treat tubercu losis and meningitis, and chitosan was obtained in the form of a film to provide co ntrolled de. Polymeric drug delivery system _____ Some interactions of natural and synthetic anionic polymers with biologically active substances Summary Anionic polymers are nowadays extensively used in.

Anionic surfactants work best to remove dirt, clay, and some oily stains. These surfactants work following ionization. When added to water, the anionic surfactants ionize and have a negative charge.

The negatively charged surfactants bind to positively charged particles like clay. Anionic surfactants are effective in removing particulate soils [11]. Nonionic surfactants are particularly efficient at removing.

Polymer therapeutics is a term used to describe an increasingly important area of biopaharmaceutics in which a linear or branched polymer chain behaves either as the bioactive (a polymeric drug) or, more commonly, as the inert carrier to which a therapeutic is covalently linked, as in the case of polymer-drug conjugates, polymer-protein conjugates, polymeric micelles, and multicomponent by: Anionic addition polymerization is a form of chain-growth polymerization or addition polymerization that involves the polymerization of monomers initiated with anions.

The type of reaction has many manifestations, but traditionally vinyl monomers are used. Often anionic polymerization involves living polymerizations, which allows control of structure and composition. Drug Deliv, ; 23(9): –. Informa UK Limited, trading as Taylor & Francis Group.

DOI: / RESEARCH ARTICLE Novel anionic polymer as a carrier for CNS delivery of anti-Alzheimer drug Satya Lavanya Jakki1*, Yasam Venkata Ramesh1*, K.

Gowthamarajan1, V. Senthil1, Kunal Jain2, Sumeet Sood3 and Deepa Pathak4. When used cationic polymers such as Eudragit® RS (EUD) and chitosan (CS) allow a greater interaction of drug with the cell membrane. While hydrophilic polymers such as polyethylene glycol (PEG) reduce recognition by the mononuclear phagocytic system, making the circulation time longer [ Cited by: 1.

Novel anionic polymer as a carrier for CNS delivery of anti-Alzheimer drug. Drug Delivery: Vol. 23, No. 9, pp. Cited by: 6. INTRODUCTION. Polymers have a wide range of applications in the field of therapeutic development.

This article describes polymer drugs in which a polymeric species directly effects the desired pharmacology, and the polymer itself is considered to be the active pharmaceutical by: 4.

pharmaceutical polymers including polyethylene glycol (PEG), polyvinyl alcohol, polyethylene oxide, polyvinyl pyrrolidone, polyacrylate or polymethacrylate esters, cellulose-based polymers.

Surfactants – classification, features and applications Surfactants – classification, features and applications N. Denkov and S. Tcholakova Department of Chemical Engineering, Faculty of Chemistry, Sofia University, Sofia, Bulgaria Lecture at COST P21 Training School “Physics of droplets: Basic and advanced topics”.

As a representative polymeric surfactants, block copolymers consisting of a PEO chain (A) and a polypropylene (PPO) chain (B) have been thoroughly exist various combinations of A and B, typically diblock AB and triblock ABA.

A range of molecular structures can be tuned by the degree of polymerization of A and B. Hydrophilic ABA-type polymer surfactants are used in commercial. In contrast to pharmacologically inert polymers used in most drug delivery applications, polymeric drugs are polymers that exhibit pharmacological activity that can be harnessed for therapeutic benefits.

Polymeric drugs have a long history, going back to the s when the first example of a polymeric drug entered clinical by: Title:Novel Salted Anionic-Cationic Polymethacrylate Polymer Blends for Sustained Release of Acidic and Basic Drugs VOLUME: 14 ISSUE: 1 Author(s):Wasfy M.

Obeidat, Duaa Qasim, Ali Nokhodchi, Ahmad Al-Jabery and AL-Sayed Sallam Affiliation:Department of Pharmaceutical Technology, Faculty of Pharmacy, Jordan University of Science and Technology, P.O. Box:IrbidAuthor: Wasfy M. Obeidat, Duaa Qasim, Ali Nokhodchi, Ahmad Al-Jabery, AL-Sayed Sallam.

As the pH value of different microenvironments may vary in living body, pH‐sensitive polymers have been employed as drug delivery systems, aiming at site‐specific drug release. The ionization/deionization of the polymers depends on the pH value of the environment, which leads to the change of polymer : Xintao Shuai, Du Cheng.

1. Introduction. Polymeric carriers have been applied in drug delivery to improve circulation time, alter biodistribution, reduce metabolism, and facilitate cellular internalization of drug cargo [, ].The pharmacokinetics of polymeric carriers and their cargo depend on polymer properties including molecular weight, dispersity, charge, functionalization, and self-assembled size and shapeCited by: 1.Cellulose nanocrystals (CNCs) are one of the most promising natural derived nanomaterials that possess a number of advantages such as nanoscale size, rich of surface functional groups, biodegradability, low cost, and desirable biocompatibility.

Considering the above characteristics, CNCs and their composites have raised considerable research attention for various applications. On the other Author: Weimin Wan, Hui Ouyang, Wei Long, Wenfeng Yan, Mingzhen He, Hongye Huang, Shilin Yang, Xiaoyong Zhan.Abstract.

The range of polymeric systems that can be used in medication is discussed. These approaches include controlled release devices (such as erodable systems, diffusion controlled systems, mechanical systems and microcapsules), biologically active polymers (such as natural polymers, synthetic polypeptides, pseudo-enzymes, pseudo-nucleic acids and polymeric drugs), and Cited by: 2.